Episode

In Our Time

BBC Radio 4

Society & Culture, History

Chart Positions

Society & Culture 60
History 20

Melvyn Bragg and guests discuss the history of ideas

Website

Penicillin

June 9th, 2016

Episode 506 of 522 episodes

Melvyn Bragg and guests discuss penicillin, discovered by Alexander Fleming in 1928. It is said he noticed some blue-green penicillium mould on an uncovered petri dish at his hospital laboratory, and that this mould had inhibited bacterial growth around it. After further work, Fleming filtered a broth of the mould and called that penicillin, hoping it would be useful as a disinfectant. Howard Florey and Ernst Chain later shared a Nobel Prize in Medicine with Fleming, for their role in developing a way of mass-producing the life-saving drug. Evolutionary theory predicted the risk of resistance from the start and, almost from the beginning of this 'golden age' of antibacterials, scientists have been looking for ways to extend the lifespan of antibiotics. With Laura Piddock Professor of Microbiology at the University of Birmingham Christoph Tang Professor of Cellular Pathology and Professorial Fellow at Exeter College at the University of Oxford And Steve Jones Emeritus Professor of Genetics at University College, London Producer: Simon Tillotson.

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